![]() ![]() The NHLBI is leading and supporting research and clinical trials to find a cure for sickle cell disease. Your healthcare team will work with you on a treatment plan to reduce your symptoms and manage the condition. Sickle cell disease is a lifelong illness. A blood and bone marrow transplant is currently the only cure for sickle cell disease, but there are effective treatments that can reduce symptoms and prolong life. The blocked blood flow through the body can lead to serious problems, including stroke, eye problems, infections, and episodes of pain called pain crises. ![]() These cells do not bend or move easily and can block blood flow to the rest of your body. If you have sickle cell disease, your red blood cells are crescent- or “sickle”-shaped. Normally, red blood cells are disc-shaped and flexible enough to move easily through the blood vessels. The condition affects more than 100,000 people in the United States and 20 million people worldwide. Transplants have a lot of side effects and can result in death when not successful.Sickle cell disease is a group of inherited red blood cell disorders that affect hemoglobin, the protein that carries oxygen through the body. They involve taking bone marrow or stem cells from the donor and implanting them into your body. They typically only are approved for severe cases. Transplants require a donor and are risky. These two treatments can cure SCD when successful. These include bone marrow and stem cell transplants. New treatment options have been introduced in recent years. ![]() If you have to travel in an unpressurized aircraft, talk to your doctor about extra precautions. They can tell you about genetic counseling and get you started with prenatal care early on. Talk to your doctor if you’re pregnant or plan to become pregnant. Manage other health issues you have, such as diabetes.This is when you stop breathing for short periods of time while you sleep. Tell your doctor if you think you have a sleep problem, such as snoring or sleep apnea.Try not to get too hot, cold, or tired.Illnesses should be treated as soon as possible. Contact your doctor if you have a fever or possible infection.Talk to your doctor if you’re depressed or have problems at home or work. Wash your hands regularly to prevent infection and illness.Drink at least eight glasses of water a day, especially in warm weather. Drink a lot of fluids when you exercise to prevent dehydration. Your doctor can help with patches, pills, and support. Visit the doctor for regular check-ups.However, there are things you can do to help prevent them. You may feel pain in your back, knees, legs, arms, chest, or stomach. This reduces the oxygen that gets to your tissues. They happen when sickle cells get stuck in your blood vessels. They can last for a few hours to a few days. Most treatment options aim to reduce symptoms and prevent complications. It’s based on your form of SCD, your symptoms, and your overall health. Treatment for SCD varies for each person. However, they can pass the sickle cell gene on to their kids. ![]() People who have this get 1 sickle cell gene from a parent and 1 normal gene from the other parent. People who have HbSS get 2 sickle cell genes, 1 from each parent.Īnother form of SCD is sickle cell trait. They vary based on the sickle cell and hemoglobin genes you inherit from your parents. When the young red cell has lost its nucleus it pauses. Sickle cells also contain an abnormal type of hemoglobin. (3) The spleen may determine the age at which the young erythrocytes are released from the bone marrow. This slows or blocks blood and oxygen to parts of your body. They can get stuck-or even burst and die-when traveling through small blood vessels. These sickle cells become hard and sticky. With SCD, some red blood cells are misshapen and look like sickles (a C-shaped farm tool). They contain hemoglobin (a protein), which carries oxygen in your blood. Normal red blood cells are round and flexible. SCD refers to a group of red blood cell disorders. It runs in families and is more common in Blacks or African Americans. Sickle cell disease (SCD) is a genetic condition you have at birth. ![]()
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